I rotate the rounds - after clearing, cleaning, or shooting at the range - the round from the chamber goes into the magazine after taking one or two out of the magazine first. I hope this reduces the chances of the setback issue from repeated loading/unloading of the same round. I'll usually shoot my self defense rounds at the range and replace what I shoot. I'll also rotate my spare mag with what is carried in the gun.
lots of options - YMMV
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