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TAM, Sig has divested itself of the Mosquito so you’re either going to find used, or as noted the GSG 1911-22 (same gun, different branding).

I had a Mosquito for a while, a later model, and as much as I’d like to say it was trouble free, it was not. So long as you fed it the HV stuff, it was ok, but SV CCI and the like would cause it to choke on a pretty regular basis. Not saying it’s a bad gun, but probably not what you’re after for a suppressor host.

P22? I’ve never owned one but only because I’ve seen enough friends enticed by them over the years only to be disappointed.

My suggestion, S&W M&P22c. It’s very close to a full size gun and actually made by S&W; careful the full size M&P22 is not, instead being made by Walther. The M&P22c is a hammer fired gun, though the hammer is shielded/enclosed. This is done as .22 ammo takes more firing pin impact than most striker fired systems can impart to ignite, especially in a smaller frame.

I have an M&P22c in my .22 pistol collection and it plays host to several of my rimfire cans. It happily eats most ammo without issue and so far has required minimal cleaning. I really owe it to that poor gun to scrub it down properly before long, but as it is I haven’t had any cleaning related stoppages so I guess it’ll go for a while longer still.