I just hate the fact that I have to keep on sliding it on and off my belt and get it just right. It's annoying and takes like 10 minutes more to get dressed in certain situations.
Have an Old Faithful SOB/MOB kit that does not require wrist twist to draw with right hand - basically a left hand holster with backward cant. About the only way I can CC a full size pistol is SOB/MOB. I do not find it uncomfortable or troublesome when seated.