I bet a bad guy would rather be sprayed than shot..
You can improve your options with both the pepper spray and the P3AT, but in your situation, I don't think getting rid of the gun is the best course of action.
Smokewagon is undoubtedly correct that a bad guy would prefer to be sprayed rather than shot, but the BG's preferences are pretty low down on the list of things that influence my tactical decisions. My point is that if I spray him (or them) with immediate attack stopping effect and create enough of an opportunity to exit the scene before they injure me, in my book I count that as a win. The effects of the OC are really quick and several BG's can be significantly impaired at almost the same time if they're close enough together. They also won't be happy and won't enjoy the experience.I did try wearing a tuckable IWB holster briefly but found this uncomfortable as well from frequent leaning, squatting and bending over. My attempt was to find a means to both carry and be comfortable at work.
The disabling effects of small caliber projectiles often take much longer (minutes instead of seconds), and rounds have to be delivered to one BG at a time while the others remain operational. In my view "much longer" is just too long. If I shoot him a couple of times with a .380 and he charges in and stabs me a couple of times with a 4 inch folder, the BG may be less happy when he finally notices he's been shot than if I'd sprayed him, but I'm in a world of hurt too. That counts as a loss in my book.
I would not suggest that OC is always better than a .380 and it is certainly not better than a handgun in a serious defensive caliber, but if concealability and carrying comfort are the overriding concerns, it's properties and effects are worth a serious look.
OC plus a firearm (my preference) is an excellent way to go because it gives you more options at different points on the use of force continuum which is always a good thing. Just remember that when the time comes for deployment, unless the situation develops so gradually that you can use them in sequence, you'll most likely have to make a choice between them because it's tough to use both at once. Decisions, decisions......
There are several deep concealment options available for txroadcyclist's situation besides IWB carry. Offside carry under the off side arm under the shirt allows one to carry a compact pistol in a serious defensive caliber with very little risk of detection, especially if one goes with shirts that are not form fitting and made of patterned material. Three good options in this category are:
Action Holsters elastic chest rig: http://actionholsters.com/
5.11 Tactical holster shirt: http://www.511tactical.com/511-holster-shirt-40011.html
Action Direct under shirt shoulder rig: http://gunnersecurity.com/holster-shoulder.html
Any of these would allow you to easily conceal a G26 or 27, 3" 1911, Kahr PM40 or PM45, or similar sized weapon and keep it very well hidden while moving, bending, etc. Big guys can effectively conceal a full size 1911 if they want to. You could, of course, also carry a smaller caliber gun this way as well, but it wouldn't make a lot of sense to me to do so when a tactically superior option is available.
The draw stroke from these rigs is not quite as fast as IWB carry but much faster than an ankle rig. If you wear one, you need to know that the draw stroke can be relatively easily blocked by an opponent who traps the strong arm to the erstwhile defender's chest in a close in encounter (something to keep in mind for your tactical positioning). On the other hand, the draw can be executed smoothly with only moderate movement, and it doesn't leave you standing on one leg with your teeth in the BG's optimum kicking zone like an ankle rig does. Some clever folks elect to expedite access by sewing the button from the button side of the shirt closure to the buttonhole side in the area they need to reach through, and sewing velcro to the two sides of the overlap to allow easy separation without popping buttons around the room.
Where there's a will, there's a way.