While my wife is not anti-gun in the house, she does have reservations on guns. When we got married 25 years ago, I was a reserve LEO and carried at that time. I have also hunted for all of our lives together, so she is no stranger to long guns or even handguns (loaded for self defense) in the house. When I went to get my CHL a few months ago she questioned the need to carry and was a little upset about it. I used the calm reasoning method, and that didn't work. So, I told her to just abide with me and she would see it was not a big thing.
Since I have received the license, I don't always let her know when I am and am not carrying. She has settled down and doesn't even worry about it since there have been no issues. By not constantly bringing it up and easing into things and giving her time to adjust slowly, she has grown to accept it.
One commet she made prior to my receiving my license was why would I ever even think about carrying in church. After the Colorado shootings, I mentioned 'I may have to start carrying to church.' Her response was , 'Yes, you might.' Little does she know that I already have several times!!
As G.C. said, take it slow and easy and let her adjust to being around guns and you'll be surprised how she will adapt. Even if she never wants to shoot, she will probably be OK with your doing it and guns being in the house.